Gene Drive- Malaria could be wiped out! - hrdubai.com

Breaking

hrdubai.com

We track updates of science and publish them.

Disqus

test banner

Post Top Ad

Responsive Ads Here

Post Top Ad

Responsive Ads Here

Friday 5 October 2018

Gene Drive- Malaria could be wiped out!

According to new research malaria mosquitoes can be wiped out



London reuter’s scientists have succeeded in wiping out a population of caged mosquitoes in laboratory experiments using a type of genetic engineering know as a Gene Drive, which spread a modification blocking female reproduction.
A report published in the journal nature biotechnology, says scientists managed to eliminate the population in less than 11 generations, the technique in future could be used to control the spread of malaria, a parasitic disease carried by Anopheles gambiae mosquitoes.
The results mark the first time this technology has been able to completely suppress a population. The hope is that in future, mosquitoes carrying a gene drive could be released spreading female infertility within local malaria- carrying mosquito population and causing them to collapse.

Gene drive technologies alter DNA and drive self-sustaining genetic changes through multiple generations by overriding normal biological processes. The technologies can be very powerful, but they are also controversial, since such genetically engineered organisms released in to the environment could have an unknown and irreversible impact on the ecosystem.
The technology used in this study was designed to target the specific mosquito species Anopheles Gambiae that is responsible for malaria transmission in sub-Saharan Africa.
The World Health Organization has warned that global progress against malaria is stalling and could be reversed if momentum in fight to wipe out was lost.
Scientists stated the results showed the gene drive solution can work, offering hope in the fight against a disease that has plagues mankind for centuries., however there are still more work to be done in both terms of testing the technology in larger lab-based and working for affected countries.


Malaria is life- threatening disease. It’s typically transmitted through the bite of an infected Anopheles mosquito. Infected mosquitoes carry the plasmodium parasite. When this mosquito bites, the parasite is released in to the bloodstream.

Once the parasites are inside the body, they travel to the liver, where they mature. After several days, the mature parasites enter the bloodstream and begin infecting red blood cells.
Within 48 to 72 hours, the parasites inside the red blood cells multiply causing to burst open.
The parasites continue to infect red blood cells, resulting in symptoms that occur in cycles that last two to three days at a time.

The Home of the Disease Mosquitos
Malaria is typically found in tropical and subtropical climates where the parasites can live. The World Health Organization (WHO) states that, in 2016, there were an estimated 216 million cases in 91 countries.  And killed 445,000 of them. Most malaria deaths are in babies and young children.
In the U.S, the centers for disease control and prevention (CDC) report 1,700 cases of malaria annually. Most cases of malaria develop in people who travel to countries where malaria is more common.

types of malaria mosquitos
there are four kinds of malaria parasites that can infect human:
1. plasmodium vivax

2. p. ovale
3. p. malariae 
4. p. falciparum
Note – p falciparum causes a more severe from of the disease and those who contact this form of malaria have been higher risk of death. An infected mother can also pass the disease to her baby at birth. This is known as congenital malaria.

Malaria can also be transmitted through:
- An organ transplants

- A transfusion
- Use of shared needles or syringes.
Conclusion
Malaria is one the most dangerous life threating infection, therefore to solve the malaria crises scientists should focus on the least risky and most effective solutions, not experiment with ecosystems with little regard for the potentially new environmental and health consequences.




No comments:

Post a Comment

Post Top Ad

Responsive Ads Here